https://lcscs12345.r-universe.devRecent package updates in lcscs12345R-universehttps://github.com/lcscs12345.pnghttps://lcscs12345.r-universe.devTue, 28 Apr 2026 13:06:05 GMTlim.bioinfo@gmail.com (Chun Shen Lim)Differential open reading frame (ORF) translation analysis framework for ribosome profiling (Ribo-seq) with matched RNA-seq. Implements (i) Differential ORF Usage (DOU), a beta-binomial generalized linear model that models the expected proportion of Ribo-seq versus RNA-seq reads mapping to each ORF within a gene, and (ii) ORF-level Differential Translation Efficiency (DTE), a negative binomial GLM that capture changes in translation efficiency of individual ORFs across experimental conditions. Supports ORF-level read summarization for bulk and single-cell Ribo-seq.https://github.com/r-universe/bioc/actions/runs/38380860470Tue, 28 Apr 2026 13:06:05 GMTDOTSeq1.1.0successhttps://bioc.r-universe.devhttps://github.com/bioc/DOTSeqDOTSeq.RmdDOTSeq.htmlDOTSeq: Detecting Differential ORF Usage in Ribosome Profiling Data2025-08-17 07:37:552026-03-17 07:14:35